By Perminder Sachdev
This quantity presents the 1st accomplished account of the clinical and scientific features of akathisia and comparable syndromes resembling stressed legs syndrome (RLS), other kinds of motor restlessness, and neuroleptic-induced dysphoria. the main target is on drug-induced akathisia and its a number of subtypes. the writer explores its courting to the restlessness because of different neurological problems, provides a brand new synthesis of the pathophysiological mechanisms of akathisia, and offers arguments for brand spanking new operational standards for the examine analysis of drug-induced akathisia. innovations for the dimension of akathisia also are mentioned, as are remedy ways. The booklet could be relatively helpful for psychiatrists, neurologists, and different physicians looking a greater realizing of those disabling syndromes.
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Extra info for Akathisia and Restless Legs
It usually occurred in the first week of treatment (Pohl et al, 1988) and, in some patients, a dose as small as 10 mg imipramine was sufficient to cause it. Zitrin et al (1980) reported it in 20% of agoraphobic women treated initially with a 25-mg/day dosage of imipramine. Pohl et al (1988), in a systematic study of the phenomenon, reported it in 49 of 158 panic disorder patients, usually developing at The anatomy of restlessness 35 dosages less than 75 mg/day and occurring more frequently with desipramine.
If the restlessness is characterized by reckless behaviour, low frustration tolerance, irritability and temper tantrums and is associated with behaviours that break basic rules or violate the rights of others, conduct disorder is diagnosed. Schachar et al (1981) reported that 3% of boys in a semirural area had this problem. Rutter et al (1975) reported that the rates in an inner-city area were twice as high. In a child psychiatry clinic, 75% of boys and 50% of girls referred for aggressive conduct disorder were also hyperactive (Stewart et al, 1981).
Time axis: Present. Item selection: Based on the Psychological Impairments Rating Schedule (Jablensky, 1978). Revised edition contains more precise definitions, reducing overlap between items and additional items regarding other commonly observed aspects of behaviour. Number of items: 97. Item definitions: Behaviours rated on 3point scale of frequency or severity, depending on the individual item; overall impression rated on 5-point scale of severity for each category. Psychometric validity: Face validity high.